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Triamterene interferes with the fluorescent measurement of quinidine, resulting in erroneous values of the serum quinidine concentration. Triamterene is a member of the drug class potassium-sparing diuretics. Triamterene may cause a spurious elevation in serum lactate dehydrogenase concentrations. Triamterene does not cause your body to lose potassium the way that many diuretics do. These products could cause your potassium levels to get too high while you are taking triamterene. Hyperkalemia may complicate any of the following conditions: chronic renal failure, systemic acidosis, such as diabetic acidosis, acute dehydration, extensive tissue breakdown as in severe burns, adrenal insufficiency, or the administration of a potassium-sparing diuretic (eg, spironolactone, triamterene, amiloride) (see OVERDOSAGE).
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